Effect of cadmium chloride on testis of Heteropneustes fossilis and recovery by herbal compound Ashawagandha

Abstract

The present study was carried out to evaluate the safe dose of cadmium chloride on the testis of Heteropneustes fossilis which were kept in aqueous solution of cadmium chloride of 0.5 ppm for 7,14 and 21 day. The histological effect of cadmium chloride in testis is characterized by regression after 7 day of exposure and spermatocytes in the seminiferous lobule showed cytololysis in 14 days duration. After 21 days, almost all the cells in seminiferous lobules were degenerated. The size of all spermatoganic cells significantly (p< 0.001) increased. Extensive damage in germinal epithelium, different spermeogenic cells and interstial cells were recovered after administration of Ashawagandha.