Effect of cadmium chloride on kidney of Heteropneustes fossilis and their recovery by herbal compound mulethi

Abstract

The present study was conducted to investigate the effect of cadmium chloride on kidney of fresh water fish Heteropneustes fossilis. The fish were exposed to 0.5 ppm of cadmium chloride (safe dose) for 7, 14 and 21 days. The most remarkable changes in kidney due to cadmium chloride were loosening of haemopoietic tissue; hemorrhagic conditions and degeneration of haemopoietic tissue. Renal tubules have lost their original appearance, wide spaces and oedema were visible in renal tubules, narrowing of tubular lumen, vacuolated cytoplasm and damaged glomeruli. The size of haemopoietic tissue and glomerulus was significantly (p<0.001) increased after treatment and the size of renal tubules significantly (p<0.05) reduced after treatment. All these changes will be recovered by herbal compound, mulethi. The damaged tissues of haemopoietic, renal tubules and glomerulus were recovered in already treated group.